Etiology and pathogenesis of insulin-dependent diabetes mellitus

[report of the Workshop on etiology and pathogenesis of insulin-dependent diabetes mellitus, Philadelphia, September 8-10, 1977
  • 48 Pages
  • 2.24 MB
  • English
National Institute of Arthritis, Metabolism, and Digestive Diseases , Bethesda, Md
Diabetes -- congr
Statementco-sponsored by National Institute of Arthritis, Metabolism, and Digestive Diseases and Juvenile Diabetes Foundation].
ContributionsJuvenile Diabetes Foundation., National Institute of Arthritis, Metabolism, and Digestive Diseases.
LC ClassificationsRC660 W6 1977, RC660 W6 1977
The Physical Object
Paginationxi, 48 leaves :
ID Numbers
Open LibraryOL21849932M

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research by: 1.

The autoimmune Etiology and pathogenesis of insulin-dependent diabetes mellitus book of human insulin-dependent diabetes mellitus (IDDM) was suspected in the early s when it was discovered by Bottazzo et al. (1) that a majority of IDDM patients harbored islet cell-specific autoantibodies (ICA) at the onset of the disease.

We shall see that such autoimmune origin is now firmly established, even if other nonimmunologic factors are also implicated in disease etiology and by: 6. Nerup 1, Christy M1 PIaH P, et al: Aspects of the genetics of insulin-dependent diabetes mellitus, in Andreani D, Di Mario U, Federlin KF, et al (eds): immunology m Diabetes.

London, Kimpton Cited by:   Twenty papers from a symposium held in October in Toronto: islet structure and function, etiologic factors, insulin receptors, counter-regulatory hormones, epidemiology, and animal models of insulin-dependent diabetes.

A closing summary of present views and future developments. Workshop on Etiology and Pathogenesis of Insulin-Dependent Diabetes Mellitus ( Philadelphia). Etiology and pathogenesis of insulin-dependent diabetes mellitus. [s.l.: s.n., ?] (OCoLC) Material Type: Conference publication: Document Type: Book: All Authors /.

The concept that diabetes mellitus is not a single disease. but rather a clinical syndrome characterized by inappropriately elevated fasting or post-prandial blood glucoses and the development of long-term microvascular, macrovascular, and neuropathic changes is of very recent origin and stems from numerous investigations into the epidemiology, genetics, etiology, and pathogenesis of clinical Cited by:   However, the inheritance of non-insulin-dependent diabetes and insulin-dependent diabetes appears to be different.

Nearly % of offspring pf parents who both have non-insulin-dependent diabetes develop that type of diabetes, but only 45% to 60% of the offspring of both parents who have insulin-dependent diabetes will develop the disease. Diabetes mellitus is a heterogeneous disorder.

About 80% of the patients with this disease are categorized as having non-insulin-dependent diabetes mellitus, a disorder resulting from varied degrees of insulin resistance and impaired insulin secretion; the causes for these abnormalities are by: role of the adipocyte in the pathogenesis of type 2 diabetes mellitus The majority (>80%) of type 2 diabetics in the US are overweight ().

Both lean and especially obese type 2 diabetics are characterized by day-long elevations in the plasma free fatty acid concentration, which fail to suppress normally following ingestion of a mixed meal or Cited by:   Etiology & pathogenesis of Diabetes Mellitus 1.

Etiology, pathogenesis,Etiology, pathogenesis, classification, early diagnosisclassification, early diagnosis and clinical presentation ofand clinical presentation of Diabetes MellitusDiabetes Mellitus 2. THE pathogenesis of diabetes mellitus has long been an enigma.

Because of its familial pattern of transmission and the subtle chronicity of the disease, diabetes has been considered a degenerative Cited by: COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Abstract. It is only within the past decade that there has been a widespread realization of the extent to which epidemiological studies can contribute toward a better understanding of the etiology, pathogenesis, and natural history of diabetes by: Nutritional composition ofStevia rebaudiana, a sweet herb, and its hypoglycaemic and hypolipidaemic effect on patients with non-insulin dependent diabetes mellitus.

Journal of the Science of Food and Agriculture, Vol. 96, Issue. 12, p. Insulin resistance, largely caused by obesity and physical inactivity, both precedes and predicts type 2 diabetes.

Details Etiology and pathogenesis of insulin-dependent diabetes mellitus PDF

The insulin resistance preceding type 2 diabetes is commonly referred to as the metabolic syndrome. The latter condition consists of a cluster of risk factors, which are thought to be either causes or consequences of insulin resistance.

Diabetes has emerged as the largest epidemic in the recent times and people often wonder about diabetes etiology and pathogenesis. In the recent times, a concept has emerged that diabetes mellitus is not a single disease but rather a bunch of symptoms which are characterized by inappropriately elevated fasting and after meal blood glucose levels.

Type 2 diabetes mellitus (DM2) results from the interaction betw een genetic and environ mental factors which cause insulin resist ance (IR) and de ficit in insulin secretion.

Download Etiology and pathogenesis of insulin-dependent diabetes mellitus FB2

Clinician's Guide to Non-Insulin-Dependent Diabetes Mellitus: Pathogenesis and Treatment: Medicine & Health Science Books @ hor: Gerald M. Reaven. etiology, pathogenesis and pathophysiology via literature review.

Diabetes is a group of metabolic Type 2 diabetes, also called non-insulin dependent diabetes mellitus (NIDDM), is caused by decreased sensitivity of target tissues to insulin. The reduced sensitivity to insulin is often called insulin.

Diabetes results in abnormal levels of glucose in the bloodstream. This can cause severe short-term and long-term consequences ranging from brain damage to ampu-tations and heart disease (ADA, ). Root causes of diabetes mellitus (DM) The root causes of diabetes are complex. Most cases begin with one of two processes.

Etiology of Type 2 Diabetes Mellitus Type 2 Diabetes mellitus (formerly called non - insulin dependent diabetes mellitus (NIDDM) or adult - onset diabetes mellitus) is a disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency.

Description Etiology and pathogenesis of insulin-dependent diabetes mellitus PDF

Circulating endogenous insulin is sufficient to. • List factors pertaining to the etiology and pathogenesis of diabetes mellitus. • Recognize criteria relevant to the diagnosis of diabetes mellitus. • Describe complications associated with diabetes mellitus.

• Discuss concepts related to dental intervention, education and treatment planning of patients with diabetes mellitus. The pathophysiology of diabetes mellitus is very complex, as this ailment is characterized by different etiologies while sharing similar signs, symptoms, and complications.

Diabetes Mellitus: Pathophysiology. The pathophysiology of all types of diabetes is related to the hormone insulin, which is secreted by the beta cells of the pancreas.

Type 1 (Insulin-Dependent) Diabetes Mellitus: Etiology, Pathogenesis, Prediction, and Prevention. Published on 28/03/ by admin. Filed under Endocrinology, Diabetes and Metabolism. Last modified 28/03/ (LADA), or slowly progressive insulin-dependent diabetes mellitus.

Diabetes Mellitus I. Etiology and Pathophysiology • Type I – insulin dependent, total defecit of circulating insulin • Type 2 – non insulin dependent, not enough insulin available to lower glucose levels • Pre-Diabetic – early stages • Gestational - pregnancy II. INTRODUCTION. Type 1A diabetes mellitus results from autoimmune destruction of the insulin-producing beta cells in the islets of Langerhans [ 1 ].

This process occurs in genetically susceptible subjects, is probably triggered by one or more environmental agents, and usually progresses over many months or years during which the subject is asymptomatic and euglycemic.

Insulin Dependent Diabetes Mellitus; OGTT: Oral Glucose Tolerance Test According to the World Fact book report inin Africa the Pathogenesis and Pathophysiology of Diabetes Mellitus There is a direct link between hyperglycemia and physiological & behavioral responses. Whenever there is hyperglycemia, the brainCited by: Diabetes Mellitus: A Review on Pathophysiology, Current Status of Oral Medications and Future Perspectives Article (PDF Available) in Acta Pharmaceutica Sciencia 55(1) April with.

Type 2 diabetes mellitus is the most common form of diabetes and is currently a major worldwide cause of morbidity and mortality. This is likely to worsen, given the rapidly increasing prevalence of this condition; therefore, an understanding of its etiology and pathogenesis is of considerable importance.

Pancreas - IDDM, insulin dependent diabetes mellitus, type 1. Onset at age. This page includes the following topics and synonyms: Type 1 Diabetes Mellitus, Type I Diabetes Mellitus, Insulin Dependent Diabetes Mellitus, IDDM, Type I Diabetes.INTRODUCTION.

Type 2 diabetes mellitus is characterized by hyperglycemia, insulin resistance, and relative impairment in insulin secretion. It is a common disorder with a prevalence that rises markedly with increasing degrees of obesity [].The prevalence of type 2 diabetes has risen alarmingly in the past decade [], in large part linked to the trends in obesity and sedentary lifestyle [].

The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions.

Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach.